Gmail Auto-Reply Draft with OpenAI Assistant – n8n Automation Template

October 14, 2025

Aladuddin Aladin

This workflow automates the process of drafting email replies in Gmail using the power of OpenAI Assistant. It checks for incoming emails with specific labels, retrieves the latest message in a thread, and sends the content to OpenAI for generating a suggested reply. The AI-generated draft is then converted into HTML, encoded, and added back to the Gmail thread as a draft. Finally, the trigger label is removed to prevent duplicate processing.

Ideal for professionals and teams who want to speed up email communication while maintaining high-quality, AI-assisted responses.

✨ Features

  • Automated Email Processing: Scans Gmail threads with specific labels at scheduled intervals.
  • AI-Powered Replies: Generates intelligent draft responses with OpenAI Assistant.
  • Seamless Gmail Integration: Creates drafts directly in the same Gmail thread.
  • Smart Content Handling: Converts Markdown to HTML for properly formatted replies.
  • Duplicate Prevention: Automatically removes trigger labels after creating drafts.
  • Configurable Schedule: Runs on a customizable interval (default: every 1 minute).
  • Clean Workflow: Handles thread fetching, message extraction, encoding, and draft creation end-to-end.

About the author

Alauddin Aladin is an AI Automation expert helping businesses streamline operations, boost productivity, and scale effortlessly using tools like Make.com and n8n. With over a decade of experience in digital systems and automation strategy, Alauddin empowers entrepreneurs to save time and grow smarter through intelligent workflows and AI-driven solutions.

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